Secretory cargo that cannot fold properly in the ER are selectively targeted for removal by a well-studied ER-associated degradation pathway. or ERAD. In contrast. very little is known about post-ER quality control mechanisms for damaged or misfolded integral membrane proteins. https://www.spidertattooz.com/Caramilk-Pumpkin-Latte-Soy-Melt-handcrafted-in-Aotearoa-New-Zealand-from-sustainable-sources-approx-40-hours-fragranc/